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There is a horde of weapons hidden in Resident Evil 4 Remake, from pistols and shotguns to knives and rocket launchers. But what are the cream of the crop, the pièce de résistance? Here are the best weapons in RE4 Remake that you should definitely go out of your way to get your hands on.
Best RE4 Weapons, Ranked

you will find seven types of weapons through León’s adventure through rural Spain: pistols, magnums, rifles, machine guns, shotguns, knivesand special weapons.
The following list is ordered by better to worse so you can find the most useful weapons in RE4 Remake weapon easily according to ammo capacity, effectivenessand strength.
Level | Weapon |
S | Red9, Blacktail, Killer7, Stingray, LE 5, Striker, Fighting Knife |
TO | SG-09R, Broken Butterfly, TMP (with stock), Primal Knife |
B. | Matilda (with stock), CQBR, Riot Gun, Combat Knife |
C. | Sentinel Nine, SR M1903, W-870, Boot Knife, Bolt Launcher |
D. | Punisher, Skull Shaker, Kitchen Knife, Rocket Launcher |
Related: Is it worth buying Sentinel Nine and Skull Shaker in Resident Evil 4 Remake?
The best pistol RE4 Remake
He red9 it’s the best pistol in the game, it ranks first in our S-tier ranking. Why? Because he’s so powerful, he can take out most mob enemies with a single well-placed headshot, when others can take two or three. Once you get the shares, you become a force to be reckoned with.
Best RE4 Remake magnum
He killer7 It comes equipped with a laser sight for maximum accuracy, which means it can pop heads with ease. It also has higher base stats compared to other magnums in Resident Evil 4 Remake, making it the best magnum to use.
Best RE4 Remake Rifle
He Stingray it is the best rifle in RE4 Remake. It has a 3x damage multiplier against enemy weak points and is the best weapon to use at medium and long range. It also supports multiple scopes.
Best RE4 Remake Submachine Gun
He LE 5 SMG has an incredibly high rate of fire and damage output, making it the perfect choice when facing off against waves of enemies. It’s also scope compatible, which means you can shred from a distance.
Best RE4 Remake Shotgun
Possibly the best type of weapon in the game, the best shotgun choice is the Striker. Combine its wide shot with the fact that it is a semi-auto and you have a clear winner against the crowds. It also has the benefit of 2x ammo capacity when upgraded, making it a certified hit, quite literally.
Best RE4 Remake Knife
If yours are knives, the combat knife it is the best choice based purely on its damage output. It has decent durability at 1.40, but expect to repair it as often as the other knives.
For more information on Resident Evil 4 Remake, check out all Castle Gate Blue Medallion Locations in Resident Evil 4 Remake on MyFullGames.
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